Ependymoma

FACTS

  • GTR is #1 association with survival
  • peak age 10-15 yrs, M = F
  • account for 60% of intramedullary spinal tumors (usually at filum)
  • typically infratentorial

HPI

Focused Exam

IMAGING

MRI Brain w/wo
  • lobulated, circumscribed, cystic, moderate enhancement, Ca2+ (50%)
  • rarely invasive (usually circumscribed with overlying ependyma)
 

A/P

Pathology

  • Gross path: tan-red
  • IHC: GFAP, PTAH