CT angiography

Allergic Reaction Preparations

• use for allergies or renal insufficiency

• prenisone or solumedrol (methylprenisolone) starting 24h prior

• Benadryl IM 1 hour or IV 4 min) prior

• +/- H2 antagonists

Radiocontrast-induced nephropathy

• IV saline hydration 24hr before and after

• 600 mg acetylcysteine PO BID 24h before and after exposure

• fenoldopam (dopamine-1 receptor, dopamine-1 agonist)

• source of sulfhydryl groups →converted into metabolites capable of stimulating  glutathione  synthesis, promoting  detoxification,  and  acting  directly  as  free radical scavengers.

• inhibits ACE, which has been shown to be involved in experimental RIN.