Disease | Pathology |
AVM | abnormally high flow often causes ectatic remodeling of the veins draining the AVM or of the arteries feeding it |
Cerebral amyloid angiopathy | amyloid fibril accumulation in small-medium sized arteries |
Cavmals / Angiomas | irregular venous-type channels lined by flat endothelium surrounded by scant smooth muscle |
Hypertension | degeneration of intima media →fragmentation of arterial smooth muscle → lipohyalinosis, fibrinoid necrosis of subendothelium, microaneurysms, focal dilatations in arteriols |
Hypoxic ischemic encephalopathy | pseudolaminar necrosis |
Primary CNS vasculitis | transmural inflammation, vessel wall injury |
Sturge-Weber Syndrome | pseudolaminar Ca2+ of neocortex, cortical atrophy underneath leptomeningeal angiomatosis |
Tuberous sclerosis | cortical tubers (thickened / raised occasionally dimpled gyrus) giant cells, dysmorphic neurons, gliosis, calcifications as well prominent cell loss in all cortical layers and lamination. |
Made with Bullet